Just FYI - The animation has some drug references and is a mildly off color and silly christmas rap song my friend made.
I started this animation in Adobe Animate on Astropad, then moved on in the third scene to ToonBoom Harmony on Astropad. The quality is obviously better with TBH. I didn't use my normal Wacom tablet, and now don't see a reason to even take it back off of the shelf.
I used a 12.9 iPad Pro with the Apple Pencil, and a 2014 Macbook Pro Retina with Wifi Astropad.
Learned a few technical things from exclusively using Astropad and the Mac.
First it was easy to ignore the pixel thing people talk about a bunch. I think my eyes got used to it, but mostly I focused on the hot pink line and then reviewed the finished stroke.
A point of pain was when I would focus the cursor on a canvas after focusing on a menu item, the first stroke would be a little clunky. Like the start and stop of the stroke would be missing about half the assumed line.
Another thing that took a little getting used to was the menu on the left side of Astropad not responding if the Apple Pencil was close to the iPad.
So I stopped using Astropad like my Wacom (resting my fingers on the action buttons, or hovering over them for a quick button push of an Undo or tool change) Instead I just tried to lift the Pencil up higher when I used my fingers, or just operated the buttons with the Pencil entirely. I would go back and forth on this, and never found the comfort of either one being better than the other.